Stress - inducible alternative translation initiation of human 5 6 cytomegalovirus latency protein pUL 138
نویسندگان
چکیده
8 Lora Grainger, Louis Cicchini, Michael Rak, Alex Petrucelli, Kerry D. Fitzgerald, 9 10 Bert L. Semler and Felicia Goodrum 2 11 12 Department of Immunobiology, 2 BIO5 Institute; The University of Arizona, 13 14 Tucson AZ 85721, Department of Microbiology and Molecular Genetics, 15 16 University of California, Irvine, CA 92697 17 18 19 20 21 Running Title: Alternative translation of latency determinant 22 23 Abstract Length: 249 24 Word count: 7,875 25 Figures: 8 26 Tables: 2 27 28 29 Corresponding Author: 30 31 Felicia Goodrum, Ph.D. 32 Department of Immunobiology 33 BIO5 Institute 34 1647 E. Helen St. Rm 425 35 University of Arizona 36 Tucson, Arizona 85721 37 [email protected] 38 phone:(520) 626-7468 39 Fax: 626-3478 40 Copyright © 2010, American Society for Microbiology and/or the Listed Authors/Institutions. All Rights Reserved. J. Virol. doi:10.1128/JVI.00855-10 JVI Accepts, published online ahead of print on 30 June 2010
منابع مشابه
Stress-inducible alternative translation initiation of human cytomegalovirus latency protein pUL138.
We have previously characterized a 21-kDa protein encoded by UL138 (pUL138) as a viral factor inherent to low-passage strains of human cytomegalovirus (HCMV) that is required for latent infection in vitro. pUL138 is encoded on 3.6-, 2.7-, and 1.4-kb 3' coterminal transcripts that are produced during productive and latent infections. pUL138 is encoded at the 3' end of each transcript and is prec...
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